Beijing Hotgen Biotech Co.,Ltd.

UPTquik® NT-proBNP Kit

Full  name: N-terminal pro B-type natriuretic peptide

UPTquik®  NT-proBNP  is an accurate, rapid, fully quantitative test used on UPTquik®  Reader for the determination of the N-terminal fragment of brain-type  natriuretic peptide in human serum, plasma and whole blood as an aiding tool for  screening, diagnosis and risk assessment of life-threatening heart failure  (HF). 

NT-proBNP: A proven  biomarker for heart failure 

The N-terminal  pro B-type natriuretic peptide  (NT-proBNP) is a 76 amino  acid N-terminal inactive protein that is cleaved from proBNP to release brain  natriuretic peptide.

The  plasma concentrations of both BNP and NT-proBNP are typically increased in  patients with asymptomatic or symptomatic left ventricular dysfunction and is  associated with coronary artery disease and myocardial ischemia. As the latter  is more stable and has higher concentration and a longer shelf life in blood,  NT-proBNP is a much better biomarker and used much more  often.

Early  diagnosis of heart failure is key to improve patient outcome. Using NT-proBNP  can help clinicians optimize management of patients with dyspnea in the  emergency room. This has shown to result in significant cost savings for  healthcare structures due to shorter stays in the emergency department and  reduced patient re-hospitalization.

International  guidelines recommend the use of B-type natriuretic peptide testing in the  diagnostic workup of Heart Failure (HF) in both acute and non-acute patient  presentation.

Benefits  of NT-proBNP test in summary:

• Diagnosis  of patients with suspected CHF
• Risk  stratification of patients with HF
• Risk  stratification of patients with ACS
• Assessment  of increased risk for cardiovascular events and mortality in patients at risk  for HF who have stable coronary artery disease  (CAD)

UPTquik® NT-proBNP Kit Test  Principle

Up-converting  Phosphor Technology

UPTquik® NT-proBNP Kit Features

• Fully  quantitative NT-proBNP measurement
• Rapid,  accurate, lab quality results within minutes
• Ready-to-use  reagents
• Serum,  plasma and whole blood are applicable as sample
• Long  shelf life
• Easy  storage at room temperature
• Single  dose format: run only the test you need