Beijing Hotgen Biotech Co.,Ltd.

UPTquik®  Procalcitonin Kit

UPTquik®  Procalcitonin  is an accurate, rapid, fully quantitative test used on UPTquik®  Reader for the determination of the procalcitonin (PCT) in human serum, plasma  and whole blood as an aiding tool for diagnosing and controlling the treatment  of severe, bacterial infection and sepsis.

PCT: A specific marker  of severe bacterial infection and sepsis  

Procalcitonin  (PCT) is a peptide precursor of the hormone calcitonin, the latter being  involved with calcium homeostasis. It is composed of 116 amino acids and is  produced by parafollicular cells (C cells) of the thyroid and by the  neuroendocrine cells of the lung and the intestine.

The  level of PCT in the blood stream of healthy individuals is below the limit of  detection (0.01 ng/mL) of clinical assays.  The level of procalcitonin rises  rapidly (within 6 – 12 hours) in a response to a proinflammatory stimulus,  especially of bacterial origin. It does not rise significantly with viral or  non-infectious inflammations. Therefore, PCT helps differentiate bacterial from  viral infections, the early detection of an elevated PCT level in patients with  suspected bacterial infections enabling earlier antibiotic treatment. PCT also  supports informed decisions on when to continue or stop antibiotics, improving  patient care and decreasing antibiotic misuse and  resistance.

 Benefits  of PCT test in summary:

• Use  as an early and specific biomarker for severe bacterial infection and  sepsis
• Assess  severity of infection and make prognosis
• Differentiate  bacterial from viral and non-infectious inflammation
• Guide  the application of antibiotics and reduce unnecessary usage of  antibiotics
• Monitor  treatment efficacy of antibiotics

UPTquik® Procalcitonin Kit Test  Principle

• Up-converting  Phosphor Technology

UPTquik® Procalcitonin Kit Features

• Fully  quantitative measurement
• Rapid,  accurate, lab quality results within minutes
• Ready-to-use  reagents
• Serum,  plasma and whole blood are applicable as sample
• Long  shelf life
• Easy  storage at room temperature
• Single  dose format: run only the test you need